BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3. The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins. Corepressor SMRT Binds the BTB/POZ Repressing Domain of the LAZ3/BCL6 Oncoprotein BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6鈥塷ncoprotein Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases. The Keap1-BTB Protein Is an Adaptor That Bridges Nrf2 to a Cul3-Based E3 Ligase: Oxidative Stress Sensing by a Cul3-Keap1 Ligase Pintard, L. et al. The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. Nature 425, 311-316 The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transc...
